Test for quantitative determination of the total activity
of alkaline phosphatase (EC 126.96.36.199.) from blood, serum,
or plasma using Reflotron.
Alkaline phosphatase (ALP) is present in various human tissues, e.g. liver, bone,
intestine and placenta. The most frequent causes of elevated total ALP activity
in serum are diseases of the liver and biliary tract. When measured together with
other enzymes such as GOT, GPT and γ-GT, ALP permits the differential-diagnostic
identification of cholestatic disorders. Elevated levels of ALP are found in various
types of bone disease and disorders of bone metabolism; e.g. Paget’s disease,
osteomalacia, rickets, hyperparathyroidism. Elevated ALP levels in malignant disorders
may be due either to the presence of tumour phosphatases or to elevation
of hepatic and bone ALP.
Increased osteoblastic activity such as that occurring in the skeletal growth phases
of childhood and adolescence is associated with ALP levels that are elevated but
fall again following puberty. Elevated levels of alkaline phosphatase observed
during the third trimester of pregnancy are produced particularly by the placental
Available in a tube of 30 test/strips.